IQ GENETIC TECHNOLOGY LIMITED × HKRM Lab Joint Product
+852 1234 5678 info@juvguard.com

JuvGuard Products

hUCMSC-Derived Exosome Nebulization · GMP Manufacturing · Designed for Pulmonary Nodules & Fibrosis

Core Product

JuvGuard
Stem Cell Exosome Nebulization

JuvGuard is a stem cell exosome nebulization product co-developed by IQ GENETIC TECHNOLOGY LIMITED and HKRM Laboratory, specifically designed for the repair and improvement of pulmonary nodules and pulmonary fibrosis.

Key Ingredient
hUCMSC-Derived Exosomes
Concentration
≥10 Billion Particles/mL
Growth Factors
450+ Active Factors
Quality Standard
PIC/S GMP Certified
Culture Process
AOF Animal-Free
Per Course
12B Exosomes (60ml)
Inquire & Order
💊

JuvGuard

Stem Cell Exosome Nebulization

≥100亿
Particles/mL
450+
Growth Factors
PIC/S GMP · A/B Grade Sterile
Mechanism

Four Core Mechanisms Working Together

🎯

Precision-Targeted Delivery

Receptors such as CXCR4 on the exosome surface recognize fibrosis/inflammation foci in the lungs, actively accumulating in damaged areas for precise treatment.

Low Systemic Toxicity High Target Concentration CXCR4 Receptor
🛡️

Anti-Inflammatory & Immunomodulation

Suppresses pro-inflammatory factors TNF-α, IL-6, IL-1β; induces M1→M2 macrophage polarization; regulates the lung immune microenvironment.

TNF-α Inhibition IL-6 Downregulation M2 Polarization
🔬

Tissue Repair & Regeneration

Carries key growth factors HGF, EGF, FGF, VEGF to stimulate alveolar epithelial cell proliferation, repairing damaged alveoli and interstitial structures.

HGF/EGF Alveolar Regeneration Interstitial Repair
💊

Anti-Fibrotic Reversal

Downregulates TGF-β expression, reduces excessive collagen deposition, blocks "scarring" progression, with clinical evidence showing reversal of established fibrotic lesions.

TGF-β Inhibition Anti-Fibrosis Reversible
Specifications

Rigorous Quality Standards

Core Ingredients & Technical Parameters

Key Ingredient Human Umbilical Cord MSC-Derived Exosomes (hUCMSC-EVs)
Technology Source HKRM Lab + Japan BMS MHLW-Certified Stem Cell Center Patent
Quality Standard PIC/S GMP Certified + A/B Grade Sterile Suite
Culture Process Animal-Origin Free (AOF) medium, chemically defined, no xenogeneic protein contamination
Concentration ≥10 Billion Particles/mL
Growth Factors 450+ types (including TIMP1, EGF, HGF and other key repair factors)
Per Treatment Course 12 Billion Exosomes (60 ml)
Storage Frozen at -80°C, valid for 12 months

Key Growth Factors

HGF
Hepatocyte Growth Factor
Promotes alveolar epithelial repair
EGF
Epidermal Growth Factor
Stimulates cell proliferation
FGF
Fibroblast Growth Factor
Tissue repair and remodeling
VEGF
Vascular Endothelial Growth Factor
Vascular regeneration and repair
TIMP1
Metalloproteinase Inhibitor
Inhibits fibrosis progression
miRNA-21
Regulatory microRNA
Anti-inflammatory signaling
TGF-β受体
Growth Factor Receptor
Fibrosis signal interception
IL-10
Anti-inflammatory Interleukin
Immune balance regulation
How to Use

Simple Operating Procedure

Nebulization Inhalation Steps

1
Thaw
Remove exosome supernatant from freezer and allow to thaw naturally at room temperature for 2 hours (do not heat or microwave)
2
Inspect
Confirm packaging is intact with no leaks, solution is clear with no turbidity
3
Mix
Pour normal saline into nebulizer cup, add thawed supernatant, and gently swirl to mix
4
Nebulize
Turn on nebulizer, breathe slowly and deeply through the mouthpiece for approximately 10–15 minutes until liquid is consumed
5
Clean
Immediately clean all nebulizer components after use and allow to air dry

Important Precautions

  • Use thawed supernatant within 24 hours
  • Do not use if solution becomes turbid, has sediment or unusual odor
  • For nebulization inhalation only — do not swallow or inject

Recommended Treatment Schedule

Standard Treatment Protocol
Single Dose 1ml (~1 billion exosomes)
Frequency Once per week
Recommended Cycle 5 weeks per course
Maintenance Once every 3 months

Expected Improvement Timeline

7 Days
Cough and shortness of breath begin to ease
2–4 Weeks
FVC and MVV lung function indicators begin improving
4–8 Weeks
Breathing difficulty eases, activity tolerance increases
3–6 Months
Imaging shows lesion absorption / fibrosis reduction
Indications

Who is Suitable for JuvGuard

Pulmonary Fibrosis

✅ Idiopathic Pulmonary Fibrosis (IPF)
✅ Interstitial Lung Disease (ILD)
✅ COPD with fibrosis
✅ Post-COVID pulmonary fibrosis
✅ Post-pneumonia fibrosis

Pulmonary Nodules

✅ Inflammatory & ground-glass nodules
✅ Post-COVID multiple nodules
✅ Small nodules in long-term smokers
✅ Chronic bronchitis with multiple nodules
✅ Residual nodules after infection

High-Risk Prevention

✅ Long-term smoking / secondhand smoke
✅ Mildly reduced lung function
✅ Compromised immune system
✅ Recurrent respiratory infections
✅ Sub-optimal lung function

Contraindications / Defer Use

❌ Acute upper/lower respiratory infection ❌ Acute exacerbation of ground-glass nodules ❌ Lesions above the main bronchus ❌ Known allergy to product components ❌ Severe liver or kidney dysfunction ❌ Confirmed malignant lung cancer (consult physician)

Find the Right Dosage Plan for You

Each patient's lung condition is different — our professional team will tailor a personalized treatment recommendation

Free Consultation View Research Data
Consult